Fort Myers is a larger medium-sized coastal city (i.e. on the ocean, a bay, or inlet) located in the state of Florida. With a population of 97,372 people and 86 associated neighborhoods, Fort Myers is the 33rd largest community in Florida. Much of the housing stock in Fort Myers was built relatively recently. The construction of new real estate can often be taken as an indication that the local Fort Myers economy is robust, and that jobs or other amenities are attracting an influx of new residents. This seems to be the case in Fort Myers, where the median household income is $57,403.00.

A relatively large number of people in Fort Myers telecommute to their jobs. Overall, about 9.64% of the workforce works from home. While this may seem like a small number, as a fraction of the total workforce it ranks among the highest in the country. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Fort Myers is also nautical, which means that parts of it are somewhat historic and touch the ocean or tidal bodies of water, such as inlets and bays. Such areas are often places that visitors and locals go for waterfront activities or taking in the scenery.

The overall education level of Fort Myers citizens is substantially higher than the typical US community, as 31.30% of adults in Fort Myers have at least a bachelor's degree, and the average American community has 21.84%.

The per capita income in Fort Myers in 2022 was $38,217, which is middle income relative to Florida, and upper middle income relative to the rest of the US. This equates to an annual income of $152,868 for a family of four. However, Fort Myers contains both very wealthy and poor people as well.

Fort Myers is an extremely ethnically-diverse city. The people who call Fort Myers home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Fort Myers residents report their race to be White, followed by Black or African-American. Fort Myers also has a sizeable Hispanic population (people of Hispanic origin can be of any race). People of Hispanic or Latino origin account for 23.69% of the city’s residents. Important ancestries of people in Fort Myers include German, Irish, English, Italian, and Haitian.

Foreign born people are also an important part of Fort Myers's cultural character, accounting for 20.35% of the city’s population.

The most common language spoken in Fort Myers is English. Other important languages spoken here include Spanish and French Creole.